Thursday, June 27, 2013

General Information On EPM In Horses

By Lila Barry


Equine protozoal myeloencephalitis, also known as simply EMP, is the name of a disease that occurs in horses. EPM in horses is the result of a protozoal infection in the central nervous system of these animals. A doctor named Jim Rooney first discovered it in the mid twentieth century.

EPM is generally considered a rare condition. In more recent times, a high occurrence of cases has been reported. Research work was performed at the University of Kentucky. The results found that opossum is the definitive host for this specific disease.

Sarcocystis neurona and Neospora hughesi are the two responsible parasites for EPM. Very little is know about Neospora hughesi, especially its life cycle. On the other hand, Sarcocystis neurona involves two hosts to complete a life cycle. There must be a intermediate host and a definitive host. Sea otters, raccoons, cats, skunks and armadillos have been show, in labs, to function as intermediate hosts.

As stated, opossum is the definitive host for EPM. Usually horses get this disease from watering or grazing in locations near where possums have recently defecated. These animals are unable to pass the disease alone. That is, one horse that is infected cannot pass it on to another horse that is not. The horse is a dead-end host of the parasites.

There are certain symptoms caused by this condition. Some of the most common signs is asymmetric incoordination, spasticity and weakness. Although the symptoms may mimic nearly any neurologic disorder. Overall, symptoms may be classified as primary or secondary. Some signs are more difficult to categorize from other problems. Other symptoms to look for when identifying this problem: laryngeal hemiplegia, snoring, and muscle atrophy of some sort.

Little is known about how the Sarcocystis neurona actually enters into the CNS of the animal. Still, it is believed that it infects the white blood cells so that it can cross into the blood brain barrier. This disease can be treated, but in some cases, horses may experience irreversible system damage.

It is crucial that the problem be identified early on so that treatment can be issued, in the form of antiprotozoal drugs. There are currently two treatments available that have been approved by the FDA for use in the US: Marquis, Protazil. To limit potential damage to CNS and reduce any inflammation, anti-inflammatory medicines are often prescribed. Using antioxidants can help with restoring the nervous tissue. To control or prevent this condition, owners are encourage to correctly store horse hay and feed, control the opossums in an area and quickly dispose of carcasses. These is not a vaccine for this available on the market.

EPM in horses is considered a rare disease. During the 1960s, Jim Rooney discovered the disease, which is known to attack the central nervous system of horses. The condition is the result of two different parasites. There are numerous symptoms and signs to look for when diagnosing the problem. Animals that are treated promptly are known to fully recover, but in some cases irreversible damage may be done to the nervous system of the animal.




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